Caution: Retinol can cause significant irritation, redness and peeling, especially around the eyes and mouth, in the early stages of treatment while skin builds tolerance. If you have not used high-strength retinol formulas in the past, we strongly recommend that you start your retinol regimen with our Retinol 0.2% in Squalane and adjust to higher strengths of Retinol 0.5% in Squalane and Retinol 1% in Squalane as your skin builds tolerance. You will achieve the same end results without the unpl Note: Water can affect the stability of retinol. Additionally, plant oils in retinol formulations can trigger lipid peroxidation and can impair retinol integrity. This formula does not contain water, silicones, plant oils or alcohol. Caution: Retinoids can make the skin more sensitive to UV radiation. Sun protection is particularly important when using retinoids. This product must not be used in conjunction with other retinoids including retinol or retinoic acid. This product is not a treatment for acne. Acne-prone skin may experience a temporary increase in acne during the first few weeks of using any form of retinoid including those used in this formulation. Note: When pregnant or breastfeeding, it is recommended to avoid any skincare products containing retinoids such as formulations with Granactive Retinoid or Retinol. International products have separate terms, are sold from abroad and may differ from local products, including fit, age ratings, and language of product, labeling or instructions.