Product Description
Clinical Studies and Therapies in Parkinson's Disease
Translations from Preclinical Models
A comprehensive review of the problems in the translation of preclinical outcomes to clinical studies and new pharmacological therapies
Juan Segura-Aguilar (Author)
9780128221204, Elsevier Science
Paperback / softback, published 16 June 2021
306 pages
22.9 x 15.2 x 2 cm, 0.45 kg
More than 50 years have passed since the use of L-dopa in the palliative treatment of Parkinson\u2019s disease, but it remains the most common treatment despite inducing severe side effects such as dyskinesia after 4\u20136 years of use. Numerous preclinical investigations based on endogenous neurotoxin models have promised various therapies for Parkinson\u2019s disease, but these efforts have failed when attempting to transfer these successful results to preclinical studies. Although several publications have warned of these failures, the scientific community remains mostly unaware, and there is a]
Clinical Studies and Therapies in Parkinson's Disease Segura-Aguilar Paperback
Clinical Studies and Therapies in Parkinson's Disease
Translations from Preclinical Models
A comprehensive review of the problems in the translation of preclinical outcomes to clinical studies and new pharmacological therapies
Juan Segura-Aguilar (Author)
9780128221204, Elsevier Science
Paperback / softback, published 16 June 2021
306 pages
22.9 x 15.2 x 2 cm, 0.45 kg
More than 50 years have passed since the use of L-dopa in the palliative treatment of Parkinson\u2019s disease, but it remains the most common treatment despite inducing severe side effects such as dyskinesia after 4\u20136 years of use. Numerous preclinical investigations based on endogenous neurotoxin models have promised various therapies for Parkinson\u2019s disease, but these efforts have failed when attempting to transfer these successful results to preclinical studies. Although several publications have warned of these failures, the scientific community remains mostly unaware, and there is a]
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