Research focused on protein folding misfolding and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact. Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments including the recognition of protein misfolding as both a marker and a causal agent the text presents the work of those who are actively pursuing more effective treatments as well as preventative measures and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals as well as the potential role of various inhibitors and NSAIDS. A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding Divided into five sections this groundbreaking text provides up-to-date accounts for Alzheimer’s Parkinson’s Huntington’s Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors including oxidative stress play a role in these complex diseases. | Protein Misfolding in Neurodegenerative Diseases Mechanisms and Therapeutic Strategies