an impressive text that addresses a glaring gap in the teaching of physical chemistry being specifically focused on biologically-relevant systems along with a practical focus…. the ample problems and tutorials throughout are much appreciated. –Tobin R. Sosnick Professor and Chair of Biochemistry and Molecular Biology University of Chicago Presents both the concepts and equations associated with statistical thermodynamics in a unique way that is at visual intuitive and rigorous. This approach will greatly benefit students at all levels. –Vijay S. Pande Henry Dreyfus Professor of Chemistry Stanford University a masterful　tour de force…. Barrick's rigor and scholarship come through in every chapter. –Rohit V. Pappu Edwin H. Murty Professor of Engineering Washington University in St. Louis This book provides a comprehensive contemporary introduction to developing a quantitative understanding of how biological macromolecules behave using classical and statistical thermodynamics. The author focuses on practical skills needed to apply the underlying equations in real life examples. The text develops mechanistic models showing how they connect to thermodynamic observables presenting simulations of thermodynamic behavior and analyzing experimental data. The reader is presented with plenty of exercises and problems to facilitate hands-on learning through mathematical simulation. Douglas E. Barrick is a professor in the Department of Biophysics at Johns Hopkins University. He earned his Ph. D. in biochemistry from Stanford University and a Ph. D. in biophysics and structural biology from the University of Oregon. | Biomolecular Thermodynamics From Theory to Application